KPV 10mg - UPA

Anti-Inflammatory Peptide • Immune Response Research • Cellular Signalling Studies

KPV (Lysine-Proline-Valine) is a naturally occurring tri-peptide derived from the Alpha-Melanocyte-Stimulating Hormone ($\alpha$-MSH). In the world of research and optimization, it is highly regarded as a potent anti-inflammatory and antimicrobial agent without the typical side effects of melanocortins (like skin darkening).

Key Benefits in Research

• Systemic Anti-Inflammatory: KPV works by inhibiting pro-inflammatory cytokines. It is a primary subject in studies involving IBS/IBD (Crohn’s and Ulcerative Colitis) due to its ability to soothe the gut lining.

• Skin Health & Wound Healing: In dermatological research, it is studied for its ability to reduce symptoms of psoriasis and eczema, as well as its antimicrobial properties against pathogens like Staphylococcus aureus.

• Mast Cell Stabilizer: It is often investigated for its role in stabilizing mast cells, making it a point of interest for research into Histamine Intolerance or Mast Cell Activation Syndrome (MCAS).

• Non-Melanotropic: Unlike its parent molecule ($\alpha$-MSH), KPV does not bind to the MC1R receptor, meaning it does not cause changes in skin pigmentation.

Dosing & Reconstitution

KPV is highly versatile and is often researched via subcutaneous injection, oral capsules (for gut health), or topical creams.

• Subcutaneous Research Dose: Common research protocols often utilize 200mcg to 500mcg per day.

Storage & Stability

Peptides are delicate, and KPV is no exception. To maintain the integrity of the Life-OS batches, follow these guidelines:

• Lyophilized Powder (Pre-mix):

  • Room Temp: Stable for 3–4 weeks (good for shipping).

  • Refrigerator (2°C–8°C): Stable for up to 24 months.

  • Freezer (-20°C): Stable for several years.

• Reconstituted (Post-mix):

  • Must be refrigerated. Once mixed with BAC water, it should be used within 30–60 days.

  • Avoid Light: Store in a dark place or an opaque vial box to prevent UV degradation.